Abstract We examine the collider signatures of a WIMP dark matter scenario comprising a singlet fermion and an SU(2) n-plet fermion, with a focus on n = 3 and n = 5.The singlet and n-plet masses are of the order of the electroweak scale.The n-plet contains new charged particles which will be copiously pair-produced at the LHC.Small mixing angles an
Effect of TP53 deficiency and KRAS signaling on the bioenergetics of colon cancer cells in response to different substrates: A single cell study
Metabolic reprogramming is a hallmark of cancer.Somatic mutations in genes involved in oncogenic signaling folk rivet sweat pathways, including KRAS and TP53, rewire the metabolic machinery in cancer cells.We here set out to determine, at the single cell level, metabolic signatures in human colon cancer cells engineered to express combinations of a
Bio-inspired adhesive hydrogel for wound healing
Wound healing introduces a series of interesting challenges in healthcare, such as open wounds, burn wounds, and chronic infection wounds.Hence more accurate and effective biomedical materials are expected, for which emerging hydrogels with unique and excellent properties have demonstrated great potential.When they are applied as wound dressings, t
Harnessing the Power of Onco-Immunotherapy with Checkpoint Inhibitors
Oncolytic viruses represent a diverse class of replication competent viruses that curtail tumor growth.These viruses, through their natural ability or through genetic modifications, can selectively replicate within tumor cells and induce cell death while leaving normal cells intact.Apart from the direct oncolytic activity, these viruses mediate tum
Chemical Composition and Antibacterial Activity of Liquid and Volatile Phase of Essential Oils against Planktonic and Biofilm-Forming Cells of Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen causing life-threatening, hard-to-heal infections associated with the presence of a biofilm.Essential oils (EOs) are promising agents to iphone 14 price texas combat pseudomonal infections because of the alleged antimicrobial activity of their volatile fractions and liquid forms.Therefore, the pur